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Amoxicillin fights bacteria in the body. Clavulanate potassium is a form of clavulanic acid. Augmentin is a penicillin antibiotic. Augmentin contains a combination of amoxicillin and clavulanate potassium. Amoxicillin is an antibiotic in a group of drugs called penicillins.
Generic for Augmentin and Augmentin to treat infections of the respiratory tract (including sinusitis, otitis media, recurrent tonsillitis, bronchitis and pneumonia), genitals, urinary tract, abdominal region, skin and soft tissue, and dental region.
What is Augmentin?
BRAND NAME: Augmentin, Augmentin XR, Clavam, Amoxicillin, Clamoxyl, Imacillin, Larotid, Moxacin, Novamoxin, Penamox, Robamox, Wymox
GENERIC NAME: Amoxicillin and Clavulanic Acid / Clavulanate / Co-Amoxiclav
STORAGE: Augmentin Tablets and dry powder should be stored at room temperature below 25 C (77 F), the former in a tightly closed container. Diluted powder should be refrigerated and discarded after 10 days.
PREPARATIONS: Tablets: 250mg/125mg (amoxicillin/clavulanic), 500mg/125mg, and 875mg/125mg. Chewable tablets: 125mg/31.25mg, 200mg/28.5mg, 250mg/62.5mg, and 400mg/57mg. Extended-release tablets:1000mg/62.5mg. Powder for Suspension: 125/31.25, 200/28.5, 250/62.5, 400/57, and 600/42.9 per 5 ml.
MANUFACTURERS: GlaxoSmithKline, Alkem
AVAILABLE: AUGMENTIN and Generic for Augmentin - Clavam
Augmentin comes in packs of 12 or 24 film coated tablets.
Each tablet of Augmentin (Clavamel, Synermox, Clavamox, Augmentine) contains 500 mg amoxicillin and 125 mg clavulanic acid.
Augmentin (amoxicillin & clavulanic acid) is an active antibiotic agent against most bacteria that cause common infections.
Augmentin is indicated for treatment of bacterial infections at the following sites:
- Respiratory tract infections, such as sinusitis, otitis media, recurrent tonsillitis, acute exacerbations of chronic bronchitis and pneumonia.
- Genito-urinary tract and abdominal infections.
- Skin and soft tissue infections and dental infections.
It is also indicated orally following therapy initiated intravenously in hospital to treat infection.
What is the most important information about Augmentin?
Do not use Augmentin if you are allergic to amoxicillin or clavulanate potassium, or if you have ever had liver problems caused by this medication. Do not use if you are allergic to any other penicillin antibiotic.
Before taking Augmentin, tell your doctor if you have liver disease kidney disease, or mononucleosis, or if you are allergic to a cephalosporin antibiotic, such as cefdinir (Omnicef), cefprozil (Cefzil), cefuroxime (Ceftin), cephalexin (Keflex), and others.
If you switch from one tablet form to another, take only the new tablet form and strength prescribed for you. This medicine may not be as effective or could be harmful if you do not use the exact tablet form your doctor has prescribed. Augmentin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Augmentin can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control to prevent pregnancy while taking Augmentin.
Generic Augmentin Dosage : How should take Augmentin?
Since both the 250mg and 500mg tablets of AUGMENTIN contain the same amount of clavulanic acid (125mg, as the potassium salt), two 250mg tablets of AUGMENTIN are not equivalent to one 500-mg tablet of AUGMENTIN; therefore, two 250mg tablets of AUGMENTIN should not be substituted for one 500mg tablet of AUGMENTIN.
The usual adult dose is one 500-mg tablet of AUGMENTIN every 12 hours or one 250-mg tablet of AUGMENTIN every 8 hours. For more severe infections and infections of the respiratory tract, the dose should be one 875-mg tablet of AUGMENTIN every 12 hours or one 500-mg tablet of Generic AUGMENTIN every 8 hours.
Patients with impaired renal function do not generally require a reduction in dose unless the impairment is severe. Severely impaired patients with a glomerular filtration rate of < 30 mL/min. should not receive the 875mg - tablet. Patients with a glomerular filtration rate of 10 to 30 mL/min. should receive 500mg or 250mg every 12 hours, depending on the severity of the infection. Patients with a less than 10 mL/min. glomerular filtration rate should receive 500mg or 250mg every 24 hours, depending on severity of the infection.
Hemodialysis patients should receive 500 mg or 250 mg every 24 hours, depending on severity of the infection. They should receive an additional dose both during and at the end of dialysis.
Hepatically impaired patients should be dosed with caution and hepatic function monitored at regular intervals.
Pediatric patients weighing 40 kg or more should be dosed according to the adult recommendations.
What are the possible side effects of Augmentin?
The side effects of this medication are usually of a mild nature and in general affect the digestive system (diarrhea, nausea, vomiting, indigestion, etc.). These gastrointestinal side effects may be reduced or even disappear by taking this medication at the start of meals. Consult your doctor if these symptoms are ongoing or become severe, or in the case of persistent diarrhea.
Adverse reactions, which include the following symptoms, may also occur: skin rash with or without itching, swelling of the face and difficulty in swallowing. If any of these symptoms occur, stop taking Augmentin and tell your doctor immediately. Hepatitis and jaundice have been reported rarely. These hepatic reactions have been reported more frequently in elderly patients and males particularly those over 65 years. The risk increases with duration of treatment longer than 14 days. Central Nervous System effects have been seen rarely. These include nervousness, dizziness, headache and convulsions.
Prolongation of bleeding time and prothrombin time has also been reported rarely.
On very rare occasions this medication may cause more serious gastrointestinal, hepatic or allergic reactions.
If you notice any other adverse reaction not mentioned in this patient information leaflet, consult your doctor or pharmacist.
Augmentin (Amoxicillin and Clavulanic Acid / Clavulanate) and Alcohol
Drinking alcohol along with medications is almost always a potential risk. Mainly because alcohol will reduce your own defense system and cause stress to your body when it is otherwise already stressed. But it is also an obvious depressant so it complicates things by causing increased sedation and reduced mentation. Many medications also contribute to this effect and the result can be additive. Finally, alcohol is metabolized through the liver and can be rather harsh on that organs ability to handle the metabolism of any other substances. In some cases this can be very significant.
All things considered, the Augmentin alone represents a fairly low risk factor in each of these situations. Provided that you are not also taking any other medications. Provided that your infection is not severe enough to have reduced your strength and vitality. Provided that you are not one of the rare few who become sedated by Augmentin.
If you are young, vital, and otherwise healthy and you have nothing else to offer in response to my other questions then you can reasonably proceed with your intended plans. Just be careful.