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Generic for Tequin 200mg 400mg (Gatifloxacin)

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Gatifloxacin Tequin is used to treat a variety of bacterial infections. It works by stopping the growth of bacteria. This medication belongs to a class of drugs called quinolone antibiotics. This antibiotic only treats bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness


BRAND NAME: Zymar, Gaity, Tequin

GENERIC NAME: Gatifloxacin

STORAGE: Store at 25C (77F); excursions permitted to 15 to 30 C (59F to 86F), away from moisture and light, and out of reach of children and pets.

PREPARATIONS: Tablets 200 mg and 400 mg

MANUFACTURERS: Dr. Reddy's, etc

AVAILABLE: not available


What is Gatifloxacin
Tequin is an antibiotic in a group of drugs called fluoroquinolones. It fights bacteria in the body.

Tequin is used to treat bacterial infections of the lungs, sinuses, skin, and urinary tract. It is also used to treat certain sexually transmitted diseases.

Tequin may also be used for purposes other than those listed here.

The first quinolone antibiotic to come in bioequivalent 400mg injectable and tablet formulations, this is a solution of gatifloxacin indicated for community-acquired respiratory tract infections and certain bacteria-caused sexually transmitted diseases. It was created with a unique 8-methoxy structure that seems to increase bactericidal action and lessen the rate of growth of resistance of gram-positive bacteria. Therefore, it can treat some infections that other antibiotics like penicillin cannot.

How Gatifloxacin Works
Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family. It inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.

Indications
Tablet:
Tequin is used to treat acute bacterial exacerbation of chronic bronchitis due to Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, or Staphylococcus aureus, acute sinusitis due to Streptococcus pneumoniae or Haemophilus influenzae, community-acquired pneumonia, uncomplicated urinary tract infections (cystitis), complicated urinary tract infections, uncomplicated urethral and cervical gonorrhea.

Bacteria:
Streptococcus pneumoniae (including multidrug-resistant strains, MDRSP), Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Staphylococcus aureus.

Eye drops:
Tequin solution is indicated for the treatment of bacterial conjunctivitis, used against the following bacteria: Cornyebacterium propinquum, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mitis, Streptococcus pneumoniae, Haemophilus influenzae. Contraindications
Tequin is contraindicated in people who have hypersensitivity to ingredients in Tequin or to other quinolone antibiotics, or to any of the components in this medication. Speak to a doctor if you have the following conditions: liver or kidney disease or heart problems. The safety and effectiveness in pediatric patients is unknown. This medicine may cause harm to an unborn baby. Before taking Tequin, tell your doctor if you are pregnant or plan to become pregnant during treatment. Dosage
Tablets (200 mg, 400 mg)

Acute Bacterial Exacerbation of Chronic Bronchitis:
Take 400 mg for 5 days.

Acute Sinusitis:
Take 400 mg for 10 days

Community-acquired Pneumonia:
Take 400 mg for 7-14 days.

Uncomplicated Skin and Skin Structure Infections:
Take 400 mg for 7-10 days

Uncomplicated Urinary Tract Infections (cystitis): 400 mg or 200 mg
Take a Single dose for 3 days

Complicated Urinary Tract Infections
Take 400 mg for 7-10 days

Uncomplicated Urethral Gonorrhea in Men; Endocervical and Rectal Gonorrhea in Women:
Take 400 mg, single dose.

Renal impairment: <40 mL/min 400 mg, 200 mg every day

Hemodialysis: 400 mg, 200 mg every day

Continuous peritoneal dialysis 400 mg, 200 mg every day

Eye drops (0.3% 5 ml)
The recommended initial dosage regimen for the treatment of bacterial conjunctivitis is:

Days 1 and 2: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times daily.

Days 3 through 7: Instill one drop up to four times daily while awake.

Overdose
Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a Tequin overdose may include decreased activity, slowed breathing, vomiting, tremors, or seizure (convulsions).

Missed a dose
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

SIDE EFFECTS
Nausea, diarrhea, headache, and dizziness may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using Gatifloxacin Tequin do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: numbness/tingling/weakness of arms/legs, swelling of the ankles/hands/feet, uncontrolled movements (e.g., tremors), vision changes. Tell your doctor immediately if any of these rare but very serious side effects occur: easy bruising/bleeding, fast/irregular heartbeats, fainting, mental/mood changes (including depression, rare thoughts of suicide), new signs of infection (e.g., fever, persistent sore throat), persistent nausea/vomiting, yellowing of eyes or skin, seizures, change in the amount of urine. This drug may rarely cause tendon damage (e.g., tendon rupture). Seek immediate medical attention, rest, and stop exercising if you develop joint/muscle/tendon pain or swelling.
Tequin may cause changes in blood sugar, especially in patients taking medications for diabetes. Discuss with your doctor or pharmacist about how to detect these changes and monitor your blood sugar regularly. Symptoms of high blood sugar include increased thirst and urination. Symptoms of low blood sugar include nervousness, shakiness, sweating, fast heartbeats, or hunger. Follow your doctor's instructions to treat your low blood sugar level (e.g., eat a quick source of sugar such as table sugar, honey, or candy; or drink a glass of orange juice or non-diet soda). Seek immediate medical attention if you experience symptoms of high or low blood sugar while taking this medication. This medication may rarely cause a severe intestinal condition (pseudomembranous colitis) due to resistant bacteria. This condition may occur weeks after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, stomach pain, blood/mucus in your stool. Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Tequin Gatifloxacin and/with Alcohol
Alcohol decreases the effectiveness of an Gatifloxacin.


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